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Gene therapy shows promise for severe combined immunodeficiency "D3"

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Researchers have found that gene therapy using a modified delivery system, or vector, can restore the immune systems of children with X-linked severe combined immunodeficiency (SCID-X1), a rare, life-threatening inherited condition that primarily affects boys. Previous efforts to treat SCID-X1 with gene therapy were initially successful, but approximately one-quarter of the children developed leukemia two to five years after treatment. Results from a study partially funded by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), suggest that the new vector is equally effective at restoring immunity and may be safer than previous approaches.</div>
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In SCID-X1, mutations in a specific gene prevent the development of infection-fighting T cells. The standard therapy for SCID is transplantation of blood-forming stem cells, but some patients lack a suitable donor. In gene therapy, doctors remove stem cells from the patient's bone marrow, use a vector to insert a corrected gene and then return the corrected cells to the patient. Scientists suspect that the vectors used in earlier studies may have activated genes that control cell growth, contributing to leukemia.</div>
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In the current study, nine boys with SCID-X1 underwent gene therapy using a vector engineered by the study researchers. Seven boys developed functional T cells at levels comparable to those seen in previous studies and have remained healthy for one to three years after treatment. Analyses of the children's T cells suggest that the new vector causes fewer genomic changes that could be linked to leukemia. Researchers will continue to monitor the boys for leukemia development. Of the two other boys, one died of a pre-existing viral infection shortly after receiving the therapy, and one failed to develop corrected T cells and was given a stem cell transplant from an unrelated donor.</div>
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Gene therapy shows promise for severe combined immunodeficiency "D3"

Researchers have found that gene therapy using a modified delivery system, or vector, can restore the immune systems of children with X-li...

Biotech news: Jumping Genes and Cichlids' Egg-Spots: How Evolution Creates new Characteristics "D1"

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The evolution of new traits with novel functions has always posed a challenge to evolutionary biology. Studying the color markings of cichlid fish, Swiss scientists were now able to show what triggered these evolutionary innovations, namely: a mobile genetic element in the regulatory region of a color gene. Their results have been published in the latest issue of the scientific journal<span class="Apple-converted-space"> </span><em>Nature Communications.</em></div>
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Biological evolution is in general based on the progressive adaption of traits through natural or sexual selection. However, ever so often, complex traits with completely new functions arise such as insect wings, feathers or the placenta. The evolution of such evolutionary innovations is often hard to explain relying solely on the model of progressive modification of already existing traits. Furthermore, it is largely unknown which genome modifications actually lead to evolutionary innovations.</div>
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A team of Basel researchers jointly lead by Prof. Walter Salzburger from the Department of Zoology and Prof. Markus Affolter from the Biozentrum at the University of Basel now clarified the genetic and developmental origins of an evolutionary innovation in African cichlids. The males of over 1,500 species feature conspicuous color markings on their anal fins -- so called egg-spots -- that play a central role in the mating behavior of these mouth-breeding fish. Immediately upon spawning, the female gathers up her eggs into the mouth before fertilization. The male then presents his egg-spots to which the female responds by snatching and bringing her mouth close to the male's genital opening -- only now are the eggs being fertilized inside the female's mouth.</div>
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<strong>Jumping genes</strong></div>
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The Basel biologists were able to show that the evolution of egg-spots is linked to the insertion of a mobile genetic element -- a "jumping gene" -- in the regulatory region of a newly identified pigmentation gene. These mobile elements are short DNA strings that are able to change their position within the genome and can influence the regulation of other genes</div>
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In the case of the cichlid's egg-spots, the presence of the "jumping gene" upstream of a pigmentation gene with the name fhl2b leads to an alteration in gene expression in pigmentation cells and therefore to the development of the characteristic egg-spot pattern on the male cichlids' anal fin. The scientists came to this conclusion after having induced the cichlids' genome segment containing the mobile element into zebrafish embryos. In fact, they were able to locate the according expression in a specific group of pigmentation cells. "These results illustrate once more the importance of changes in gene expression in evolution," comments Prof. Walter Salzburger the findings.</div>
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<span style="color: white;"><span style="font-size: large;"><a href="http://www.sciencedaily.com/releases/2014/10/141009091721.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fplants_animals%2Fbiotechnology+%28Biotechnology+News+--+ScienceDaily%29" target="_blank">Click here for more info. - Science Daily</a></span></span><br />
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<span style="font-size: x-small;">How to get a Job ?</span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">Dear
 job seekers, Most of you are Pharma/Medical/Biotech/Life Science 
Graduates/Post Graduates searching for jobs. There are plenty of job 
openings available, you are applying via Job portals but not getting 
hired - Do you want to know what is getting wrong?</span> </h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<u><span style="font-size: x-small;">Answers to your Questions -</span></u></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">! How to get your CV Shortlisted for interview call?</span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">Ans. Your CV must have proper format & skills exactly as per job requirement.</span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">! How to Qualify initial rounds of Interview?</span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">Ans. You must go through Job description & you must 
have proper knowledge about your job roles & responsibilities - 
Getting just a degree is not enough in current Industry scenario- You 
must have to give reason to HR, Why we should hire you?</span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">You must have to compete & for that you need mentors from Industry. </span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
<span style="font-size: x-small;">! How to qualify Technical/Operational round of Interviews?</span></h1>
<h1 class="ss-form-title" style="background-color: #57431f; color: white; margin: -15px -15px 15px; padding: 15px; text-align: left;">
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via experts who are already working in Industry, once you get practical 
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Biotech news: Jumping Genes and Cichlids' Egg-Spots: How Evolution Creates new Characteristics "D1"

The evolution of new traits with novel functions has always posed a challenge to evolutionary biology. Studying the color markings of cich...

PHARMA POSITIVE NEWS - Cipla to invest Rs 225 cr for new facility in IranThis is part of the company's strategy to expand its business in Asian countries "D9"

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<span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">The Mumbai-based pharma major<span class="Apple-converted-space"> </span></span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Cipla" style="-webkit-text-stroke-width: 0px; background-color: white; border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; margin: 0px; orphans: auto; padding: 0px; text-align: start; text-decoration: none; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" target="_blank">Cipla<span class="Apple-converted-space"> </span></a><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">Ltd has signed a definitive agreement with its existing Iranian distributor for setting up a<span class="Apple-converted-space"> </span></span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Manufacturing+Facility" style="-webkit-text-stroke-width: 0px; background-color: white; border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; margin: 0px; orphans: auto; padding: 0px; text-align: start; text-decoration: none; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" target="_blank">manufacturing facility<span class="Apple-converted-space"> </span></a><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">in
 Iran. The total contribution from the company over the next 3 years 
will include machinery, equipment, technical know-how and is expected to
 be approximately Rs 225 crore for a 75% stake.</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"> </span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">The
 proposed investment is subject to completion of certain conditions 
precedent and applicable regulatory approvals, said a statement.</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"> </span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">Cipla
 is in the process of expanding business into other Asian countries. 
Earlier, it had acquired front-end distribution firm in Sri Lanka and 
Yemen. In June, Cipla made its fifth global acquisition deal within a 
span of a year, with buying 51 per cent stake in a<span class="Apple-converted-space"> </span></span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Pharmaceuticals" style="-webkit-text-stroke-width: 0px; background-color: white; border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; margin: 0px; orphans: auto; padding: 0px; text-align: start; text-decoration: none; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" target="_blank">pharmaceuticals</a><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">manufacturing
 and distribution business in Yemen for $21 million. On June 17, it had 
acquired a 60 per cent stake in a Sri Lankan company for $14 million.</span><br />
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PHARMA POSITIVE NEWS - Cipla to invest Rs 225 cr for new facility in IranThis is part of the company's strategy to expand its business in Asian countries "D9"

The Mumbai-based pharma major Cipla Ltd has signed a definitive agreement with its existing Iranian distributor for setting up a manu...

PHARMA NEWS - Need for innovative cold chain transport solutions in pharma industry - CLICK HERE FOR FULL INFO. "D8"

<div dir="ltr" style="text-align: left;" trbidi="on">
<h1 style="-webkit-text-stroke-width: 0px; background-color: white; border: 0px; color: #1c3c65; float: left; font-family: ' Arial', Helvetica, sans-serif; font-size: 30px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; margin: 0px 0px 10px; orphans: auto; padding: 0px; text-align: left; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">
Need for innovative cold chain transport solutions in pharma industry</h1>
<div class="fs14 lineHit24 mB0" style="-webkit-text-stroke-width: 0px; background-color: white; border: 0px; color: black; float: left; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 24px; margin: 0px 0px 5px; orphans: auto; padding: 0px; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; width: 620px; word-spacing: 0px;">
<b>Drugs are highly sensitive to temperature fluctuations. Phase change materials can offer cost-effective, energy-efficient solutions for transporting medicines</b></div>
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<strong>Chatterji  |  Mumbai </strong><span class="Apple-converted-space"> </span><strong>October 7, 2014</strong><span class="Apple-converted-space"> </span>Last Updated at 17:07 IST</div>
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Prime Minister Narendra Modi, in an attempt to catch the industrial revolution which we bypassed and boost the economic turnaround of the country, recently launched the ‘Make in India’ initiative. If the industry were to lap it up, a certain vertical (read<span class="Apple-converted-space"> </span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Pharmaceutical" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">pharmaceutical<span class="Apple-converted-space"> </span></a>industry) of the manufacturing industry would grow up rapidly and India would occupy the dominant position of being one of the largest producers of<span class="Apple-converted-space"> </span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Generic+Drugs" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">generic drugs<span class="Apple-converted-space"> </span></a>in Asia. Having said that, there are serious loopholes in the system which could potentially still persist and pose as a serious threat to this pharmaceutical produce. This is because, a big chunk of this medicinal produce would lay to waste due to exposure to inappropriate temperatures during transport.<br /><br />An industrial estimate states that as much as 80% of the drugs produced in India lose their potency due to lack of handling capacity which has to ensure a<span class="Apple-converted-space"> </span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Temperature+Controlled+Logistic" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">temperature controlled logistic<span class="Apple-converted-space"> </span></a>procedure right from the packaging floor to the customer’s end. Sadly, not much is being done in this regard due to a lack of push from the Government and due to the general apathy of the pharma companies that are looking at profit maximisation but are ending up losing money on recalled goods due to unstandardised transportation procedures.<br /><br />Medicines and<span class="Apple-converted-space"> </span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Serums" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">serums<span class="Apple-converted-space"> </span></a>used to develop vaccines are highly sensitive to temperature shocks and often end up losing their potency owing to exposure to temperatures outside the acceptable range of 18ºC to 25ºC or 2ºC to 8ºC laid down by the WHO. Due to lack of standardisation there is never a sure shot way to know whether a vaccine or drug being administered to a patient is really even strong enough to fight the disease in itself.<br /><br />The only options present are<span class="Apple-converted-space"> </span><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Gel+Packs" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">gel packs<span class="Apple-converted-space"> </span></a>which is essentially water with a thickening agent packed in pouches. These gel packs though effective over a certain period of time, often pass as cheap solutions for maintaining temperature in the absence of active cooling without much adherence to any standard rules of temperature maintenance laid down by international organizations for pharma transport. Since there is effectively no temperature measuring device in place pharma transport companies essentially hoodwink the process and let this most unscientific method pass as ‘safe method of transport’ in turn escalating their profit margins.<br /><br />The other solution which comes in handy to maintain sub-zero temperatures for certain types of drugs is not just a threat to the drug in itself but poses as a serious environmental hazard - dry ice. Dry ice takes the temperature of the drug well below its acceptable level of cooling to almost -60ºC which in itself is highly unacceptable for any drug or medicine.<br /><br /><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Phase+Change+Materials" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">Phase change materials<span class="Apple-converted-space"> </span></a>or PCMs have the potential to nullify the threat posed by the existing choices of pharma transport and offer a scientific alternative to these methods. Phase change materials are chemicals that help maintain a certain required temperature range by absorbing large amounts of heat thereby acting as thermal batteries which once charged adequately can help maintain the temperature of the payload for as many as 100 hours.<br /><br />The change of phase in these substances help absorb large amounts of heat from their surroundings but owing to their high latent heat do not change their temperature hence helping to maintain the required temperature over long periods of time. Essentially pharma products are transported over 3 broad temperature ranges: +2 to +8ºC ; +18 to +25ºC and -18 to -25ºC; in each case there are PCMs of the right temperature profile which perfectly suit the application.<br /> </div>
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<img align="" alt="" class="imgCont" height="163" src="http://bsmedia.business-standard.com/_media/bs/img/article/2014-07/08/full/1404822665-1429.jpg" style="border: 1px solid rgb(221, 221, 221); float: left; margin: 0px 10px 0px 0px; padding: 1px; z-index: 0;" title="" width="218" /><div style="border: 0px; clear: both; float: left; font-style: italic; margin: 0px; padding: 10px 10px 10px 0px; width: 218px;">
Samit Jain, Director, Pluss Polymers Pvt Ltd</div>
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<span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">It is largely believed that most of the vaccines transported using gel pack or ice packs, see a temperature below zero (which is obvious). However vaccines, when subject to below +2ºC become ineffective. Has the government ever wondered the amount of money being wasted in giving vaccines which may not be as effective?</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"> </span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">Most pharmaceutical companies outsource the responsibility of transporting their produce to freight forwarder companies which operate in a fiercely competitive market and hence cut corners to carve out whatever little margin they can by compromising with the quality of transportation chain. Phase change materials can not only help maintain the requisite range of temperature but also use just 3/4</span><sup style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">th</sup><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"><span class="Apple-converted-space"> </span>of the volume of conventional gel packs thus providing a lower volumetric weight advantage to the freight forwarders and also making the payload lighter and portable on the whole.</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"> </span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">Phase change materials coupled with proper insulation can help prevent the breakage of cold chain without or with minimal exposure to higher temperatures hence ensuring the quality of the drugs being transported.</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"> </span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><div style="-webkit-text-stroke-width: 0px; background-color: white; border: 0px; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; margin: 0px; orphans: auto; padding: 0px; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">
We are increasingly heading towards high health costs. Prevention of diseases is no longer an option, but a necessity. For this, it is important that pharma and vaccine companies, voluntary adopt ethical practices in transportation of medicines and vaccines. Innovative solutions such as PCMs can genuinely contribute in ensuring drugs are maintained at the right temperature from start to end and reduce the drug wastage a few notches thus helping in reducing healthcare costs and making healthcare accessible to all.<br /> </div>
<span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">With a population the size of India serious thought needs to be paid both by pharmaceutical companies and the administrators on ways to prevent their pharmaceutical produce to go bad, so that they are in a position to tackle threats from epidemics and deadly diseases who’s threats loom large on our country’s citizens and its future. Capitalism and profits at the cost of health will cost the country dear.</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><span style="-webkit-text-stroke-width: 0px; background-color: white; color: black; display: inline !important; float: none; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;">____________________________________________________________________________________________________</span><br style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;" /><em style="-webkit-text-stroke-width: 0px; background-color: white; color: black; font-family: Georgia, 'Times New Roman', Times, serif; font-size: 14px; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: 22px; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px;"><a class="storyTags" href="http://www.business-standard.com/search?type=news&q=Samit+Jain" style="border: 0px; color: rgb(0, 0, 255) !important; cursor: pointer; margin: 0px; padding: 0px; text-decoration: none;" target="_blank">Samit Jain<span class="Apple-converted-space"> </span></a>is the Director of Pluss Polymers</em></div>
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PHARMA NEWS - Need for innovative cold chain transport solutions in pharma industry - CLICK HERE FOR FULL INFO. "D8"

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